Clinical trials

Explore our ongoing and completed clinical trials below. 

MOA
Disease state
Investigational therapy
Phase
Status
Clinical trial Phase MOA Disease state Investigational therapy Associated publications

Topical roflumilast cream (ARQ-151) atopic dermatitis study in pediatric patients (INTEGUMENT-PED)

Completed

Phase: 3 MOA: PDE4 inhibitor Disease state: Atopic dermatitis Investigational therapy: Roflumilast cream (ARQ-151)

Topical JAK1 inhibitor cream (ARQ-252) phase 2a nonsegmental facial vitiligo study

Terminated

Phase: 2a MOA: JAK1 inhibitor Disease state: Vitiligo Investigational therapy: JAK1 inhibitor cream (ARQ-252)

Topical JAK1 inhibitor cream (ARQ-252) phase 1/2b chronic hand eczema study

Completed

Phase: 1/2b MOA: JAK1 inhibitor Disease state: Chronic hand eczema Investigational therapy: JAK1 inhibitor cream (ARQ-252)

Topical roflumilast foam (ARQ-154) phase 3 seborrheic dermatitis study (STRATUM)

Completed

Phase: 3 MOA: PDE4 inhibitor Disease state: Seborrheic dermatitis Investigational therapy: Roflumilast foam (ARQ-154)

Topical roflumilast foam (ARQ-154) phase 3 scalp and body psoriasis study (ARRECTOR)

Completed

Phase: 3 MOA: PDE4 inhibitor Disease state: Scalp and body psoriasis Investigational therapy: Roflumilast foam (ARQ-154)

Topical roflumilast foam (ARQ-154) phase 2b scalp and body psoriasis study

Completed

Phase: 2b MOA: PDE4 inhibitor Disease state: Scalp and body psoriasis Investigational therapy: Roflumilast foam (ARQ-154)

Topical roflumilast foam (ARQ-154) phase 2 seborrheic dermatitis phase 2 study

Completed

Phase: 2 MOA: PDE4 inhibitor Disease state: Seborrheic dermatitis Investigational therapy: Roflumilast foam (ARQ-154)

Topical roflumilast foam (ARQ-154) phase 2 seborrheic dermatitis long-term safety study

Completed

Phase: 2 MOA: PDE4 inhibitor Disease state: Seborrheic dermatitis Investigational therapy: Roflumilast foam (ARQ-154)

Topical roflumilast cream (ARQ-151) phase 3 plaque psoriasis study (DERMIS-2)

Completed

Phase: 3 MOA: PDE4 inhibitor Disease state: Plaque psoriasis Investigational therapy: Roflumilast cream (ARQ-151) Associated publications: Effect of Roflumilast Cream Vs Vehicle Cream on Chronic Plaque Psoriasis: The DERMIS-1 and DERMIS-2 Randomized Clinical Trials

Topical roflumilast cream (ARQ-151) phase 3 plaque psoriasis study (DERMIS-1)

Completed

Phase: 3 MOA: PDE4 inhibitor Disease state: Plaque psoriasis Investigational therapy: Roflumilast cream (ARQ-151) Associated publications: Effect of Roflumilast Cream Vs Vehicle Cream on Chronic Plaque Psoriasis: The DERMIS-1 and DERMIS-2 Randomized Clinical Trials
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This website is intended for US healthcare professionals only. There may be information included that pertains to an investigational therapy or formulation that has not yet been approved for use in your country. The safety and efficacy of investigational therapies and/or formulations and/or uses have not been established. There is no guarantee that the agents will receive health authority approval or become commercially available in any country for the uses being investigated. This information is as of 7/2024 to the best of the Company’s knowledge and Arcutis assumes no obligation to update this information.

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